As we write this editorial for the last issue of Retina Today for 2020, we can’t help but look back on the unprecedented year we’ve all experienced. It started out like any other year: we were traveling to meetings, booking surgeries, accepting invitations to lecture, writing our editorial for the January/February issue, and offering input on topics and authors as we planned for the March issue. By the time we began putting together our April issue, the novel coronavirus had fully made itself known, and from then until our September issue we dedicated much of each issue to topics related to both retina and COVID-19.

The pandemic is far from over—we all know that. We also know that a vaccine seems to be on the horizon, but as retina specialists we can’t help with that. So we’ll let the epidemiologists and scientists diligently work on that. In the meantime, we will do what we do best and cover timely topics, including COVID-19, in Retina Today.

In this issue, we take a look at the retina pipeline, specifically early phase 1 and 2 studies exploring novel targets in the treatment of diabetic macular edema and AMD, later-stage trials for AMD, therapeutics for diabetic retinopathy, and extended-release polymer technologies. There are so many new agents, modalities, and technologies in clinical trials for the various conditions we treat, it’s a refreshing reminder of the positive things happening in the world.

In addition, this issue contains ongoing Aspen Retinal Detachment Society coverage; a thought-provoking article on the importance of long-term inflammation control for patients with uveitis by Robert C. Wang, MD; a fascinating case of an extramacular dome-shaped elevation referred for suspicion of circumscribed choroidal hemangioma; an exploration of how to build networks to screen for retinal disease in underserved areas; and an article by a group of doctors from Portugal who discuss how OCT angiography can reveal early changes in hydroxychloroquine therapy.

Also, be sure to take in the beauty of the images in this issue’s Visually Speaking column on page 56, where Sham Talati, MBBS, DO; Manish Nagpal, MBBS, MS, FRCS; and Navneet Mehrotra, MBBS, DNB, FRF, share the case of a patient with a choroidal mass. We’ve also brought back our 5Q column, and in this issue you’ll get to know more about Retina Today contributor Brian C. Joondeph, MD, MPS, FACS.

As we close the book on 2020, we wish you all good health and happiness, and we look forward to seeing you in 2021!