September 2006

Breaking Ground in the Treatment of Retinal Diseases

EAGLE to Study Central Retinal Artery Occlusion

The natural course of central retinal artery occlusion often leads to blindness in the affected eye.

CONNI BERGMANN KOURY, EDITOR-IN-CHIEF

Retinal Microvascular Abnormalities, Cardiovascular Mortality Linked

Future computer technology may be able to noninvasively predict target organ damage and cardiovascular risk.

ALUN D. HUGHES, mbbs, phd, bsc

Treatment of DR With Somatostatin Analogues: Where Do We Go From Here?

Previous in vitro and animal studies have identified antiangiogenic activity of this agent.

STELA S. PALII, PhD, AND MARIA B. GRANT, MD

Glycosylation Enzyme Inhibition May Provide Novel Rationale for Diabetic Retinopathy Treatment

Subclinical inflammation plays an important role in the pathogenesis of diabetic retinopathy, evidence reveals.

RAKESH CHIBBER, PhD

Pegaptanib Can Reduce Proliferative Diabetic Retinopathy Progression

Data from 10 patients presented at ARVO were very promising; additional patients will be now be studied.

CONNI BERGMANN KOURY, EDITOR-IN-CHIEF

Newer Endoilluminators Ease 25-Gauge Surgery

Using xenon-based light systems, vitreoretinal surgeons can reduce potential phototoxicity risks while performing difficult surgeries.

ALLEN C. HO, MD

Corneal Dryness Affects OCT Scan Quality

The drying effects were relatively long lasting, therefore imaging studies should be conducted before automated perimetry.

CONNI BERGMANN KOURY, EDITOR-IN-CHIEF

FDA Approved Ranibizumab for Neovascular AMD

AMD is a major cause of blindness in individuals aged ≥55 years.

CONNI BERGMANN KOURY, editor-in-chief

CFH Polymorphism May Cause More Than Half of All AMD Cases

Complement factor H is involved in early as well as late disease pathogenesis, and it markedly increases the risk of late AMD in the elderly.

PAULUS T.V.M. de JONG, MD, PhD

AMD Linked to Stroke Risk

The evidence linking AMD and stroke comes from cross-sectional studies.

TIEN YIN WONG, MD, MPH, PhD

Minimally Depressed AMD Patients Suffer Additional Declines in Vision

Depression is common among patients with AMD, and it is unlikely to be recognized or treated.

BARRY W. ROVNER, MD

PDT Beneficial in Eyes With CNV, Submacular Hemorrhage and AMD

Investigators evaluated the visual acuity results associated with PDT using verteporfin..

PAUL M. BEER, MD

Niacin Produces Vasodilation of the Retinal Arterioles

There is great interest in vasodilating compounds because of their potential therapeutic effects on ischemic ocular vascular disease.

JUAN E. GRUNWALD, MD

Clinical Trial Update: AMD

Trial: A Phase 4, Open Label, Multi-Center, Study of Maintenance Intravitreous Injections of Pegaptanib Sodium (Macugen) Given Every 6 Weeks for 48 Weeks in Subjects With Subfoveal Neovascular Age-related Macular Degeneration (AMD) Initially Treated With a Modality Resulting in Maculopathy Improvement

Understanding the Relationship Between Hyperglycemia and Microvascular Complications

Jointly sponsored by The Dulaney Foundation and Retina Today Release Date: August 2006. Expiration Date: August 31, 2007. This continuing medical education activity is supported by an educational grant from Eli Lilly and Company.

BERNARD ZINMAN, MD

5 Questions with Alan Bird, MD

Dr. Bird is a world-renowned retinal specialist who began his career at Moorfield's Eye Hospital.

Alan Bird, MD