October 2011

Preserving the Culture of Innovation in Retina

Allen C. Ho, MD Chief Medical Editor, and Robert L. Avery, MD Associate Medical Editor

Clinical Trials for the Retina Specialist

The Renaissance of Drug Delivery Systems for the Posterior Segment

ARON SHAPIRO, AND ELIOT LAZAR, MD

Fellows' Focus

Clinical Trials: The Basics of Operation and Participation

ANDRE J. WITKIN, MD; NIKOLAS J.S. LONDON, MD; AND ALOK S. BANSAL, MD; WITH CARL D. REGILLO, MD, FACS; JOEL A. PEARLMAN, MD, PHD; AND DAVID S. BOYER, MD

Retina in the ASC

Considerations When Choosing an EHR System

ARUN KAPUR

Retina Pearls: Managing Proliferative Vitreoretinopathy With Retinal Detachment

There is a high probability of anatomic success after repair.

TAREK S. HASSAN, MD

Global Perspectives: Microincisional Vitrectomy Surgery in Japan: An Update

YUICHIRO OGURA, MD

Surgicial updates: The Silicone Sandwich Technique

MARK S. MANDELCORN, MD FRSCS; EFREM D. MANDELCORN, MD FRCSC; ANDRES EMANUELLI, MD; AND THOMAS A. ALBINI, MD

Case Reports in Ocular Oncology: Combined Hamartoma of the Retina and Retinal Pigment Epithelium with Poor Visual Acuity BY

NICOLE C. BEHARRY, MD; KIRAN TURAKA, MD; AND CAROL L. SHIELDS, MD

The Evolution of Retinal Gene Therapy: From DNA to FDA

JEAN BENNETT, MD, PHD; AND ALBERT M. MAGUIRE, MD

Human Adult Umbilical Stem Cells: Potential Treatment for Atrophic AMD

A phase 1 clinical trial is assessing safety.

ALLEN C. HO, MD

Update on Laser Plus Intravitreal Ranibizumab for Diabetic Macular Edema

Two-year results of a clinical trial show continued efficacy.

THOMAS W. STONE, MD, AND TIM DONALD, ELS

Anti-VEGF Treatment for Diabetic Macular Edema

Aggressive treatment helped to control DME in the third year of follow-up in the READ-2 study.

THOMAS G. CHU, MD, PHD

Emerging Treatments for Dry AMD

A number of early clinical trials are under way.

DAVID S. BOYER, MD

Clinical Implications of Potential Therapies for Diabetic Macular Edema

Several therapies have been investigated or are in use; none are approved specifically for DME.

QUAN DONG NGUYEN, MD, MSC; DIANA V. DO, MD; DAVID S. BOYER, MD; AND JULIA A. HALLER, MD

Genetic Basis of Age-related Macular Degeneration

The Haplotype Map has elucidated the complex and polygenic basis of AMD.

JACLYN L. KOVACH, MD

Electrical Stimulation Therapy for Retinal Degeneration

Initial reactions from patients indicate major interest in this mode of therapy.

WALTER G. WROBEL, MD, PHD; GUIDO BLAESS, PHD; CARMEN EIPPER; ALEX HARSCHER, PHD; AND ANUSCH HEKMAT, PHD

New Parameters in Vitreoretinal Surgery

Safer intraoperative IOP regulation may help to avoid iatrogenic injury.

PRAVIN U. DUGEL, MD, AND DAVID BUBOLTZ, BS, MBA

Posterior Scleral Buckle for Posterior Perforating Eye Injuries

Use of radial elements for these injuries reduced rates of retinal detachment.

KRISTINE K. PIERCE, MD, AND R. GARY LANE, MD

Vitreoretinal Surgery in Anticoagulated Patients

Vitreoretinal surgery can be safely performed while maintaining warfarin anticoagulation in many patients.

M. GILBERT GRAND, MD

Advanced Imaging Technology Enhances Pediatric Ophthalmology Practice

SD-OCT case reports.

STEPHEN B. PREPAS, MD

Cooperative Competitiveness in a Multi-Practice Office- Surgery Complex

A downtown center offers synergy, efficiency.

E. MITCHEL OPREMCAK, MD

5Q With Diana V. Do, MD

Dr. Do is an Associate Professor of Ophthalmology and Assistant Head of the Retina Fellowship Training Program at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, in Baltimore, Maryland.