May/June 2025

FDA Guidance: What it Means for AMD Trials

Industry leaders discuss the shifts in clinical trial designs and their recent interactions with the FDA.

Nadia K. Waheed, MD, MPH; Ramiro Ribeiro, MD, PhD; Victor Chong, MD, MBA, FARVO; Lanita Scott, MD; and David J. Tanzer, MD

VBS 2025 Highlights: Surgical Scenarios

Experts shared their preferred surgical management approach for bilateral retinal detachments.

Lauren Kiryakoza, MD; Prashant D. Tailor, MD; and Hailey K. Robles-Holmes, MD, MPH

Expanded Transfer of Care Policies in Retina

Here’s what’s old and how to implement what’s new.

Joy Woodke, COE, OCS, OCSR

Emerging (Durable) Therapies for Wet AMD

New approaches are helping us care for patients while reducing their treatment burden.

Jacob S. Heng, MD, PhD, and Adrienne W. Scott, MD

Imaging Biomarkers for GA Progression

Our study identified a set of OCT parameters that can predict a faster growth rate.

Maxwell S. Mayeda, MD, and Talisa E. de Carlo Forest, MD

Gene Therapy for AMD: What You Need to Know

Several candidates with varying mechanisms of action and delivery methods are in clinical trials.

Szilárd Kiss, MD, FASRS, and Peyman Razavi, MD

Beyond Complement: Emerging Therapeutics for Dry AMD

Targeting inflammation, mitochondrial health, and neuroprotection.

Aumer Shughoury, MD, and Thomas A. Ciulla, MD, MBA

AI Chatbots in Retina

With proper foresight, this technology has the potential to enhance clinical efficiency and patient care.

Matteo Mario Carlà, MD, and Stanislao Rizzo, MD

Understanding—and Overcoming—Fellowship Challenges

Recent survey results can help us better understand the experiences of current and former vitreoretinal fellows.

Vicente Lorenzo Cabahug, MD, DPBO, and Andrew S.H. Tsai, MBBS, MCI, FRCOphth

Valsalva Retinopathy: The Silent Bleeder

A rare, potentially severe retinal hemorrhage can occur as a result of certain activities.

Inês Cerdeira Ludovico, MD; Patrícia Silva, MD; Joana Ferreira, MD; Ana Luísa Basílio, MD; and Carlos Batalha, MD

Implantable Drug Delivery: A Look At Pharmacokinetics

Novel approaches are showing promise for addressing treatment burden in retinal disease.

Charles C. Wykoff, MD, PhD, FASRS, FACS

Posterior Placoid Changes Due to Nutritional Deficiency

Low levels of vitamin A may be the culprit behind this ocular condition.

Eric W. Lai, MD; Brian K. Do, MD; and Sidney A. Schechet, MD

A New Technique for Myopic Traction Maculopathy

Learn about wristwatch macular buckling and how we have optimized the procedure.

Nikoloz Labauri, MD; Tekla Mamageishvili, MD; Monika Zalinian, MD; and Supriya Dabir, MD, PhD

Retina by the Numbers

Allen C. Ho, MD, and Robert L. Avery, MD